Publications

Independent Research Publications

  1. “Palladium Catalyzed Double Allylic Rearrangement of N-Alloc-N-Allyl Ynamides. Evidence for Reversible C-N Cleavage and Pd(0) Catalyzed Ketenimine Aza-Claisen Rearrangement” Juliana R. Alexander, Veronika I. Shchepetkina, Ksenia S. Stankevich, Rory Benedict, Samuel P. Bernhard, Regean Dreiling and Matthew J. Cook* Submitted for Publication

  2. “Coumarin Partitioning in Model Biological Membranes: Limitations of LogP as a Predictor” Katelyn M. Duncan, Aoife Casey, Christine A. Gobrogge, Rhys Trousdale, Stefan M. Pointek, Matthew J. Cook, William H. Steel and Robert A. Walker* J. Phys. Chem. B. 2020, In Press. DOI: 10.1021/acs.jpcb.0c06109

  3. “A Highly Selective Bi(OTf)3 Mediated Fragmentation-Contraction of δ-Ortholactones. A Facile Route to Highly Functionalized γ-Lactones” Kate L. Baddeley and Matthew J. Cook*, Tetrahedron, 2018, 74, 5172-5182. Link 

    Invited contribution: for the Sir Derek Barton Centennial Edition of Tetrahedron.


    Bi(OTf)3 Tetrahedron Graphical Abstract 1


  4. “Formation of Ketenimines via the Palladium Catalyzed Decarboxylative π-Allylic Rearrangement of N-Alloc Ynamides” Juliana R. Alexander and Matthew J. Cook*, Org. Lett. 201719, 5822–5825. Link

    ketenimine GA


  5. “A Hydrosilylation-Hiyama Approach to Highly Functionalized Dienes” Catherine A. McAdam, Mark G. McLaughlin and Matthew J. Cook*, Org. Chem. Front. 20152, 510-514. Link. 

    Invited Contribution: for the Negishi (Nobel Laureate) 80th Birthday Edition.


    org chem front 2015


  6. “Palladium Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones” Kate L. Baddeley, Qun Cao, Mark J. Muldoon*, and Matthew J. Cook* Chem. Eur. J. 201521, 7726-7730.. Link

    CEJ 2015


  7. “Base Mediated Cascade Rearrangements of Aryl Substituted Diallyl Ethers” Jolene P. Reid, Catherine A. McAdam, Adam, J. S. Johnston, Matthew N. Grayson, Jonathan M. Goodman and Matthew J. Cook*, J. Org. Chem. 201580, 1472-1498. Link

    Highlighted in: Organic Chemistry Portal.


    JOC 2015


  8. “MIDA Vinylsilanes: Selective Cross-Couplings and Applications to the Synthesis of Functionalized Stilbenes” Mark G. McLaughlin, Catherine A. McAdam and Matthew J. Cook*, Org. Lett. 201517, 10-13. Link

    Highlighted in: Organic Chemistry Portal.


    OL 2015


  9. “Silicon-Directed Rhenium Catalyzed Allylic Substitutions with N-Hydroxycarbamates, N-Hydroxysulfonamides and Hydroxamic Acids” Sanjay W. Chavhan, Catherine A. McAdam and Matthew J. Cook* J. Org. Chem. 201479, 11234-11240. Link

    CEJ 2015


  10. “Silicon-Directed Rhenium Catalyzed Allylic Carbaminations and Oxidative Fragmentations of γ-Silyl Allylic Alcohols” Sanjay W. Chanvhan and Matthew J. Cook*, Chem. Eur. J. 201420, 4891-4895. Link

    CEJ 2014


  11. “Highly Diastereoselective Hydrosilylations of Allylic Alcohols” Mark. G. McLaughlin and Matthew J. Cook*  Chem. Commun. 201450, 3501-3504. Link   

    CC 2014


  12. “NaH Mediated Isomerisation-Allylation Reaction of 1,3-Substituted Propenols” Adam J. S. Johnston, Mark G. McLaughlin, Jolene P. Reid and Matthew J. Cook*, Org. Biomol. Chem. 201311, 7662-7666. Link Open Access.

    OBC 2013 B


  13. “The Synthesis of Nitriles from Aldehydes and Aqueous Ammonia Catalysed by Copper(II)/TEMPO with Ambient Air as the Oxidant” Laura M. Dornan, Qun Cao, James C. A. Flanagan, James, J. Crawford, Matthew J. Cook* and Mark J. Muldoon*, Chem. Commun. 2013, 49, 6030 -6032. Link 

    Highlighted in: Org. Proc. Res. Dev. 201317, 994-1001.


    CC 2013


  14. “Platinum Catalysed Hydrosilylation of Propargylic Alcohols” Catherine A. McAdam, Mark G. McLaughlin, Adam J. S. Johnston, Jun Chen, Magnus W. Walter and Matthew J. Cook*, Org. Biomol. Chem. 201311, 4488 – 4502. Link Open Access.

    OBC2013 A


  15. “Palladium Catalyzed Decarboxylative Rearrangement of N-Alloc Indoles” Jun Chen and Matthew J. Cook*, Org. Lett. 2013, 15, 1088-1091. Link 

    OL 2013


  16. “The Synthesis of N-Heterocycles via Copper/TEMPO Catalysed Aerobic Oxidation of Amino Alcohols” James C. A. Flanagan, Laura M. Dornan, Mark G. McLaughlin, Niall G. McCreanor, Matthew J. Cook* and Mark J. Muldoon*, Green Chem. 2012, 14, 1281. Link Open Access

    GC 2012


  17. “Domino Alkene-Isomerization-Claisen Rearrangement Strategy to Substituted Allylsilanes” Mark G. McLaughlin and Matthew J. Cook*, J. Org. Chem. 2012, 77, 2058. Link

    Highlighted in: Synfacts 2012, 8, 527.


    JOC 2012


  18. “PtCl2/XPhos: A highly efficient and readily available catalyst for the hydrosilylation of propargylic alcohols”  Mark G. McLaughlin and Matthew J. Cook*, Chem. Comm. 2011, 47, 11104-11106. Link

    CC 2011


    Independent Review Publications

  19. “meso-3,5-Dimethyl Glutaric Anhydride” Matthew J. Cook* e-EROS: Encyclopedia of Reagents for Organic Synthesis, 2018, DOI: 10.1002/047084289X.rn02080. Link

  20. 4-Fluorostyrene” Niall G. McCreanor and Matthew J. Cook*, e-EROS: Encyclopedia of Reagents for Organic Synthesis 2012, DOI: 10.1002/047084289X.rn01450. Link

  21. “4-Trifluoromethylstyrene” Mark. G. McLaughlin and Matthew J. Cook*, e-EROS: Encyclopedia of Reagents for Organic Synthesis 2012DOI: 10.1002/047084289X.rn01451. Link


    Graduate and Postdoctoral Publications


  22. “The Catalytic Alkylative Desymmetrization of Anhydrides in a Formal Synthesis of Ionomycin” Kevin M. Oberg; Brian M. Cochran; Matthew J. Cook and Tomislav Rovis*, Synthesis 201850, In PressDOI: 10.1055/s-0037-1609733. Link

    Invited Contribution:  for the Scott Denmark 65th Birthday Edition of Synthesis


  23. “Processes for Preparing 5,7-Diaminopyrazolo[1,5-a] Pyrimidine Compounds” Dennis C. Liotta; James P. Snyder.; Ashutosh S. Jogalekar; Anthony G. M. Barrett; Matthew J. Fuchter; Matthew J. Cook; Sebastian H. B. Kroll, PTC Int. Appl. 2010, WO 2010/069938 A2 20100617. Link

  24. “Ligand Differentiated Complemtary Rh Catalysts for the Enantioselective Desymmetrization of meso Cyclic Anhydrides” Jeffrey B. Johnson, Matthew J. Cook and Tomislav Rovis*, Tetrahedron 2009, 65, 3202-3210. Link 

    Invited contribution: for the Tetrahedron Young Investigator Award 2008 to Professor Justin Du Bois.


  25. “Enantioselective Rhodium-Catalyzed Alkylative Desymmetrization of 3,5-Dimethylglutaric Anhydride”  Matthew J. Cook and Tomislav Rovis*, Synthesis 2009, 335-338. Link

  26. “Enantioslective Rhodium Catalyzed Desymmetrization of meso-3,5-Dimethyl Glutaric Anhydride: A General Strategy to syn-Polypropionate Synthons” Matthew J. Cook and Tomislav Rovis*, J. Am. Chem. Soc. 2007, 129, 9302-9303. Link 

    Highlighted in: Chem. & Ind. 2007, (16), 29-30 and Synfacts 2007, 10, 1053. Selected as: “Synfact of the Month” for Oct. 2007 & review of this work was published in Synform 2007, A81.


  27. “Microwave-Assisted, Regioselective, Petasis Olefination of Unsymmetrical Oxalates. Formation of Pyruvate Based Enol Ethers and enamines” Matthew J. Cook, Declan, W. Fleming and Timothy Gallagher*, Tetrahedron Lett. 2005, 46, 297-300. Link

  28. “Highly Stereoselective Addition of Organozinc Reagents to Pentopyranose Derived Glycals: Effect of Protecting Group and Assignment of C-Glycoside Stereochemistry” Matthew J. Cook, Matthew J. E. Fletcher, Diane Gray, Peter J. Lovell and Timothy Gallagher*, Tetrahedron, 2004, 60, 5085-5092. Link